Vortioxetine: Indications, Side Effects, Warnings - Drugs.com.

Vortioxetine is a novel antidepressant, approved by the US Food and Drug Administration (FDA) for the treatment of major depressive disorder (MDD). Because vortioxetine exhibits both an antidepressant and anxiolytic effect, it may be effective in treating both depressive and anxiety disorders, such as generalized anxiety disorder (GAD).

Vortioxetine (Trintellix) is an antidepressant used for treating a certain type of depression known as major depressive disorder (MDD). Vortioxetine decreases the reuptake of serotonin just like selective serotonin reuptake inhibitors (SSRIs). It also stimulates various serotonin receptors in the brain.

Pharmacokinetic Drug Interactions Involving Vortioxetine.

Vortioxetine (Brintellix) is a type of antidepressant. You can find detailed information about this drug in the official Patient Information Leaflet (PIL), including what it's for, how to take it, possible side effects and safety information. This leaflet should come with your medication (usually inside the box).Vortioxetine(Brintellix) generic is an antidepressant used for the treatment of major depressive disorder (MDD) in adults and also investigated as a treatment for generalized anxiety disorder (GAD).Both vortioxetine and St John's Wort can increase the risk of serotonin syndrome. See 'Serotonin syndrome' and 'Monoamine-oxidase inhibitor' under Antidepressant drugs in BNF for more information and for specific advice on avoiding monoamine-oxidase inhibitors during and after administration of other serotonergic drugs.


The starting and recommended dose of Brintellix is 10 mg vortioxetine once daily in adults less than 65 years of age. Depending on individual patient response, the dose may be increased to a maximum of 20 mg vortioxetine once daily or decreased to a minimum of 5 mg vortioxetine once daily.Vortioxetine is an SSRI (selective serotonin reuptake inhibitor) and serotonin receptor modulator. This medication may improve your mood, sleep, appetite, and energy level and may help restore your.

Vortioxetine Fluoxetine may be used for the treatment of depression and other mood disorders. It is more likely to cause insomnia than drowsiness. Prescribed for Anxiety and Stress, Major Depressive Disorder.

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Vortioxetine, sold under the trade names Trintellix among others, is a medication used to treat major depressive disorder. Effectiveness is viewed as similar to that of other antidepressants. (2) In Britain, it is only recommended in people who have not improved sufficiently on two other antidepressants. (3).

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Vortioxetine is an atypical antipsychotic and antidepressant indicated for the treatment of major depressive disorder (MDD). It is classified as a serotonin modulator and simulator (SMS) as it has a multimodal mechanism of action towards the serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin receptors and inhibits the reuptake of serotonin.

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About vortioxetine. Vortioxetine is from a new class of psychotropic drugs, the bis-aryl-sulfanyl amines, and acts on the serotonin (5-HT) system.7 Non-clinical data suggests that the drug is a 5-HT 3, 5-HT 7 and 5-HT 1d receptor antagonist, a 5-HT 1b receptor partial agonist, a 5-HT 1a receptor agonist and an inhibitor of 5-HT transporter.1 The starting dose of vortioxetine is 10mg once daily.

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Can TRINTELLIX cause sexual side effects? Based on voluntary reports, no more than 5% of patients taking TRINTELLIX in 6- to 8-week clinical studies reported sexual side effects. When proactively assessed in patients with normal sexual functioning in seven studies using a self-rated questionnaire, reports of sexual side effects from doses of TRINTELLIX 5 mg, 10 mg, 20 mg were 16%, 20%, 29% in.

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Wellbutrin (bupropion), classified as a dopamine reuptake inhibitor, is used to treat depression and seasonal affective disorder as well as a smoking cessation aid. Remeron (mirtazapine) is a noradrenergic antagonist used for major depression, that blocks receptors of the stress hormone epinephrine (adrenaline) on the brain. Oleptro (trazodone) and Brintellix (vortioxetine) are serotonin.

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ATC Classification: N06AX26 - vortioxetine; Belongs to the class of other antidepressants. Disclaimer: This information is independently developed by MIMS based on Vortioxetine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries.

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There is no information regarding presence of vortioxetine in human milk, effects on the breastfed infant, or effects on milk production; vortioxetine is present in rat milk; developmental and health benefits of breastfeeding should be considered along with mother's clinical need for therapy and any potential adverse effects on breastfed child from therapy or from underlying maternal condition.

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Side Effects. Drug information provided by: IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

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